TC-G 1004

TC-G 1004

• CAS Number: 1061747-72-5
• UNSPSC Description: TC-G 1004 (compound 16j) is an orally active A2A adenosine receptor antagonist, with Ki values of 0.44 nM and 80 nM for hA2A and hA1, respectively[1].
• Target Antigen: Adenosine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/tc-g-1004.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC(NC1=NC(N2N=C(C)C=C2C)=NC(C3=NC(N4CCC(OC)CC4)=CC=C3)=C1)=O
• Molecular Weight: 421.50
• References & Citations: [1]Xiaohu Zhang, et al. Lead optimization of 4-acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease. J Med Chem. 2008 Nov 27;51(22):7099-110.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported