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IRL 1038

CAT: 0804-HY-P1018Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1018Size:1 Each
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Description
IRL 1038 is an endothelin B receptor selective antagonist with a Ki of 6-11 nM[1].
CAS Number
144602-02-8
UNSPSC
12352209
Target
Endothelin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/irl-1038.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC1)N)=O)C(C)C)=O)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)N[C@@H](CC4=CN=CN4)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O
Molecular Formula
C68H92N14O15S2
Molecular Weight
1409.67
References & Citations
[1]Urade Y, et al. An endothelin B receptor-selective antagonist: IRL 1038, [Cys11-Cys15]-endothelin-1 (11-21) . FEBS Lett. 1992 Oct 12;311 (1) :12-6. doi: 10.1016/0014-5793 (92) 81355-p.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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