CE-1037

• Description :

  CE-1037 (MDL 201,404YA) is a selective inhibitor of human neutrophil elastase (HNE) (Ki: 0.45 nM) . CE-1037 prevents the pulmonary hemorrhage induced by intratracheal instillation of HNE. CE-1037 can be used for research of pulmonary diseases, such as COPD[1].

• Product Name Alternative :

  MDL 201,404YA

• UNSPSC :

  12352005

• Target :

  Elastase

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=S(C1=CC=C(OC(C(C2=CC=C(C(C(OC3=CC=C(S(=O)(CC(C(O)=O)(C)C)=O)C=C3)=O)(C)C)C=C2)(C)C)=O)C=C1)(CC(C)(C)C(O)=O)=O

• Molecular Formula :

  C36H42O12S2

• Molecular Weight :

  730.84

• References & Citations :

  [1]Ohbayashi H. Neutrophil elastase inhibitors as treatment for COPD. Expert Opin Investig Drugs. 2002 Jul;11 (7) :965-80.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [150493-09-7]