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RT-AM

CAT: 0804-HY-108715A-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-108715A-02Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RT-AM is a pro-agent real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
CAS Number
2280796-94-1
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/RT-AM.html
Purity
98.07
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1OC2=CC(N3CCC3)=CC=C2C=C1/C=C(C#N)/C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=O
Molecular Formula
C26H25N3O11
Molecular Weight
555.49
References & Citations
[1]Jiang X, et al. Quantitative real-time imaging of glutathione. Nat Commun. 2017 Jul 13;8:16087.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

Chemical Information

CID 134128279
CAS Number2280796-94-1
PubChem CID134128279
IUPAC Nameacetyloxymethyl 2-[[2-(acetyloxymethoxy)-2-oxoethyl]-[(E)-3-[7-(azetidin-1-yl)-2-oxochromen-3-yl]-2-cyanoprop-2-enoyl]amino]acetate
Molecular FormulaC26H25N3O11
Molecular Weight555.5
XLogP1.8
Topological Polar Surface Area179
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count13
Rotatable Bond Count15
Heavy Atom Count40
Formal Charge0
Complexity1110
SMILES
CC(=O)OCOC(=O)CN(CC(=O)OCOC(=O)C)C(=O)/C(=C/C1=CC2=C(C=C(C=C2)N3CCC3)OC1=O)/C#N
InChI
InChI=1S/C26H25N3O11/c1-16(30)36-14-38-23(32)12-29(13-24(33)39-15-37-17(2)31)25(34)20(11-27)9-19-8-18-4-5-21(28-6-3-7-28)10-22(18)40-26(19)35/h4-5,8-10H,3,6-7,12-15H2,1-2H3/b20-9+
InChIKey
CLCCMBNDDZVBCA-AWQFTUOYSA-N
Chemical Structure
2D Structure
2D structure of CID 134128279
CAS: 2280796-94-1
CID: 134128279
Formula: C26H25N3O11
MW: 555.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight555.5
XLogP31.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count13
Rotatable Bond Count15
Exact Mass555.14890862
Monoisotopic Mass555.14890862
Topological Polar Surface Area179 Ų
Heavy Atom Count40
Formal Charge0
Complexity1110
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes