AM-0561

• Description:

  AM-0561 is a NIK inhibitor (Ki: 0.3 nM) . AM-0561 decreases p52 levels[1].

• UNSPSC:

  12352005

• Target:

  NF-κB

• Related Pathways:

  NF-κB

• Field of Research:

  Cancer

• Smiles:

  C[C@] (C1=NC=CS1) (C#CC2=CN3C (C4=NC (N) =NC=C4Cl) =CN=C3C=C2) O

• Molecular Formula:

  C18H13ClN6OS

• Molecular Weight:

  396.85

• References & Citations:

  [1]Demchenko YN, et al. Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB. Oncotarget. 2014 Jun 30;5 (12) :4554-66.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1202764-63-3