AM-0561

• Description :

  AM-0561 is a NIK inhibitor (Ki: 0.3 nM) . AM-0561 decreases p52 levels[1].

• UNSPSC :

  12352005

• Target :

  NF-κB

• Related Pathways :

  NF-κB

• Field of Research :

  Cancer

• Smiles :

  C[C@](C1=NC=CS1)(C#CC2=CN3C(C4=NC(N)=NC=C4Cl)=CN=C3C=C2)O

• Molecular Formula :

  C18H13ClN6OS

• Molecular Weight :

  396.85

• References & Citations :

  [1]Demchenko YN, et al. Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB. Oncotarget. 2014 Jun 30;5 (12) :4554-66.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1202764-63-3]