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AM-9635

CAT: 0804-HY-118374Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118374Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AM-9635 is a selective PI3Kδ inhibitor with oral bioavailability, good in vitro and in vivo activity and pharmacodynamic properties. AM-9635 inhibits PI3Kδ-dependent B cell receptor-mediated AKT phosphorylation and suppresses the production of specific IgG and IgM antibodies in rats immunized with Aplysia leocyanin (KLH) .
CAS Number
1338483-10-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Akt; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/am-9635.html
Smiles
N#CC(C(N[C@H](C(N(C1=CN=CC(F)=C1)C2=C3)=NC2=CC=C3F)C)=NC=N4)=C4N
Molecular Formula
C19H14F2N8
Molecular Weight
392.36
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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