AM-9635

• UNSPSC Description:

  AM-9635 is a selective PI3Kδ inhibitor with oral bioavailability, good in vitro and in vivo activity and pharmacodynamic properties. AM-9635 inhibits PI3Kδ-dependent B cell receptor-mediated AKT phosphorylation and suppresses the production of specific IgG and IgM antibodies in rats immunized with Aplysia leocyanin (KLH).

• Target Antigen:

  Akt; PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/am-9635.html

• Smiles:

  N#CC(C(N[C@H](C(N(C1=CN=CC(F)=C1)C2=C3)=NC2=CC=C3F)C)=NC=N4)=C4N

• Molecular Weight:

  392.36

• References & Citations:

  [1]Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1338483-10-5