AM-9635

• Target:

  Others|||PI3K|||Akt

• Related Pathways:

  Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Others

• Bioactivity:

  AM-9635 is a potent and selective PI3K? inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM) . AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3K? and PI3K? are ubiquitously expressed and play a role in cell growth, division, and survival.

• Smiles:

  [C@H](NC=1C(C#N)=C(N)N=CN1)(C)C=2N(C=3C(N2)=CC=C(F)C3)C=4C=C(F)C=NC4

• Molecular Formula:

  C19H14F2N8

• Molecular Weight:

  392.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1338483-10-5