AM-9635

CAT: 0931-T70943-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T70943-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1338483-10-5

Target

Others, PI3K, Akt

Related Pathways

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Others

Bioactivity

AM-9635 is a potent and selective PI3Kδ inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM) . AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3Kα and PI3Kβ are ubiquitously expressed and play a role in cell growth, division, and survival.

Smiles

[C@H](NC=1C(C#N)=C(N)N=CN1)(C)C=2N(C=3C(N2)=CC=C(F)C3)C=4C=C(F)C=NC4

Molecular Formula

C19H14F2N8

Molecular Weight

392.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-118374	AM-9635
HI-76302W	Conductivity Probe for HI-9033 and HI-9635
BA5219-5.1	AM-6538
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B7392-100	AM 1172
B5370-1	BCECF-AM
BA5327-5	AM-1638
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HY-122007	AM-0561
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AM-9635

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