AM-8508

• CAS Number :

  1338483-67-2

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  AM-8508 is a potent and selective PI3K? inhibitor. AM-8508 showed good cellular potency (in vitro pAKT IC50 = 4.6 nM) . AM-8505 xhibited excellent HWB potency (HWB (pAKT) IC50 = 2.7 nM) . AM-8508 inhibit KLH-specific antibodies in animal models, signifying its potential for the treatment of human inflammatory diseases. PI3K? and PI3K? are ubiquitously expressed and play a role in cell growth, division, and survival.

• Smiles :

  [C@H](NC=1C(C#N)=C(N)N=CN1)(C)C=2N(C=3C(N2)=CC=C(F)C3)C=4C=CC=NC4

• Molecular Formula :

  C19H15FN8

• Molecular Weight :

  374.37

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C