LMD-902

• Description:

  LMD-902, a LMD-009 (HY-121885) analog, is a CCR8 agonist with an EC50 of 15 nM. LMD-902 has a superior binging capacity depending on key residues such as PheVI:16. LMD-902 can be used for inflammation diseases like bronchial asthma and central nervous system diseases like multiple sclerosis research[1].

• UNSPSC:

  12352100

• Target:

  CCR

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Smiles:

  O=S(NCC)(C1=CC=C(C=C1C2(CCN(CC2)CC3=CC(OC4=C(OC)C=CC=C4)=CC=C3)O)OC)=O

• Molecular Formula:

  C28H34N2O6S

• Molecular Weight:

  526.64

• References & Citations:

  [1]Jensen PC, et al. Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8. Mol Pharmacol. 2007 Aug;72 (2) :327-40.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CCR8

• CAS Number:

  [521979-59-9]