MPX-007

• Description:

  MPX-007 is a GluN2A antagonist (IC50: 27 nM) . MPX-007 is a tools to probe GluN2A physiology, and to study neuropsychiatric and developmental disorders[1].

• UNSPSC:

  12352005

• Target:

  IGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mpx-007.html

• Purity:

  99.83

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(NCC1=CN=C(S1)C)C2=NC(C)=C(N=C2)CNS(=O)(C3=CC=C(C(F)=C3)F)=O

• Molecular Formula:

  C18H17F2N5O3S2

• Molecular Weight:

  453.49

• References & Citations:

  [1]Volkmann RA, et al. MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit. PLoS One. 2016 Feb 1;11 (2) :e0148129.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1688685-29-1]