CXF-007

CAT: 0804-HY-161326Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-161326Size:1 Each
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Description
CXF-007 is a potent and specific FGFR4 inhibitor with a IC50 value of 7 nM. CXF-007 has antitumor activity[1].
CAS Number
[2727083-99-8]
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cxf-007.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(OC)=CC(N(C2)C(N(CCC3=CC=C(NC(C=C)=O)C=C3)C4=C2C=NC(NC5=C(NC(C=C)=O)C=CC=C5)=N4)=O)=C1
Molecular Formula
C34H33N7O5
Molecular Weight
619.67
References & Citations
[1]Chen X, et al. Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4. Eur J Med Chem. 2024 Feb 28;268:116281.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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