CXF-007

• Description :

  CXF-007 is a potent and specific FGFR4 inhibitor with a IC50 value of 7 nM. CXF-007 has antitumor activity[1].

• UNSPSC :

  12352005

• Target :

  FGFR

• Type :

  Reference compound

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cxf-007.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=CC(OC)=CC(N(C2)C(N(CCC3=CC=C(NC(C=C)=O)C=C3)C4=C2C=NC(NC5=C(NC(C=C)=O)C=CC=C5)=N4)=O)=C1

• Molecular Formula :

  C34H33N7O5

• Molecular Weight :

  619.67

• References & Citations :

  [1]Chen X, et al. Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4. Eur J Med Chem. 2024 Feb 28;268:116281.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2727083-99-8]