DB772 (free base)

DB772 (free base)

• CAS Number: 433735-90-1
• UNSPSC Description: DB772 free base is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 free base also has anti-prion activity[1].
• Target Antigen: Flavivirus
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/db772-free-base.html
• Smiles: C1(N=C(C2=CC=C(C3=CC=C(C4=NCCN4)C=C3)O2)N5)=C5C=CC=C1
• Molecular Weight: 328.37
• References & Citations: [1]James B Stanton, et al. Discovery of a novel, monocationic, small-molecule inhibitor of scrapie prion accumulation in cultured sheep microglia and Rov cells. PLoS One. 2012;7(11):e51173.|[2]Benjamin W Newcomer, et al. Efficacy of an antiviral compound to inhibit replication of multiple pestivirus species. Antiviral Res. 2012 Nov;96(2):127-9.|[3]Kelcey D Dinkel, et al. Antiprion Activity of DB772 and Related Monothiophene- and Furan-Based Analogs in a Persistently Infected Ovine Microglia Culture System. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5467-82.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported