WIN 62,577

CAT: 0804-HY-118356Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-118356Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WIN 62,577 is a rat-specific, but non-human, NK1 receptor antagonist. WIN 62,577 interacts with M1-M4 mAChRs and is an allosteric enhancer of acetylcholine affinity targeting the M3 receptor.
CAS Number
[144177-32-2]
UNSPSC
12352005
Target
MAChR; Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/win-62-577.html
Smiles
C[C@@]12[C@]3([H])[C@](CCC1=CC4=NC5=NC6=CC=CC=C6N5C=C4C2)([H])[C@@]7([H])[C@](CC3)([C@@](O)(CC7)C#C)C
Molecular Formula
C29H31N3O
Molecular Weight
437.58
References & Citations
[1]Analogs of WIN 62,577 Define a Second Allosteric Site on Muscarinic Receptors
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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MBS5778816WIN 62,577
MBS156168-01OST 577
PPL80021-1aPET28a-577
PVTB80021-1apET28a-577 Plasmid
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315600FAK (Ab-576/577)
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sc-24553Rsk-2 (Thr 577)

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