WIN 62,577

• Description :

  WIN 62,577 is a rat-specific, but non-human, NK1 receptor antagonist. WIN 62,577 interacts with M1-M4 mAChRs and is an allosteric enhancer of acetylcholine affinity targeting the M3 receptor.

• CAS Number :

  [144177-32-2]

• UNSPSC :

  12352005

• Target :

  MAChR; Neurokinin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/win-62-577.html

• Smiles :

  C[C@@]12[C@]3([H])[C@](CCC1=CC4=NC5=NC6=CC=CC=C6N5C=C4C2)([H])[C@@]7([H])[C@](CC3)([C@@](O)(CC7)C#C)C

• Molecular Formula :

  C29H31N3O

• Molecular Weight :

  437.58

• References & Citations :

  [1]Analogs of WIN 62,577 Define a Second Allosteric Site on Muscarinic Receptors

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported