N-Desmethyl Galanthamine

N-Desmethyl Galanthamine

• CAS Number: 41303-74-6
• UNSPSC Description: N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].
• Target Antigen: Cholinesterase (ChE)
• Type: Natural Products
• Related Pathways: Neuronal Signaling
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/n-desmethyl-galanthamine.html
• Purity: 98.96
• Solubility: DMSO : ≥ 50 mg/mL
• Smiles: O[C@H]1C=C[C@@]23CCNCC4=CC=C(OC)C(O[C@@]3([H])C1)=C24
• Molecular Weight: 273.332
• References & Citations: [1]Melanie-Jayne R. Howes, et al. Acetylcholinesterase inhibitors of natural origin. International Journal of Research in Pharmaceutical and Biomedical Sciences 3(SI 1):67-86.|[2]Bachus R, et al. The O-demethylation of the antidementia drug galanthamine is catalysed by cytochrome P450 2D6. Pharmacogenetics. 1999;9(6):661-668.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light)
• Clinical Information: No Development Reported