N-Desmethyl Eletriptan

• Description:

  N-desmethyl Eletriptan is a metabolite of Eletriptan (HY-A0039) . It is formed from eletriptan primarily by the cytochrome P450 (CYP) isoform CYP3A4 in human liver microsomes.

• UNSPSC:

  12352005

• Hazard Statement:

  H319

• Target:

  Cytochrome P450

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/n-desmethyl-eletriptan.html

• Smiles:

  O=[S](CCC1=CC=C2C(C(C[C@H]3CCCN3)=CN2)=C1)(C4=CC=CC=C4)=O

• Molecular Formula:

  C21H24N2O2S

• Molecular Weight:

  368.49

• Precautions:

  P264-P280-P305+P351+P338

• References & Citations:

  [1]Evans, et al. Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein. Drug Metab. Dispos. 31 (7), 861-869 (2003) .

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [153525-55-4]