Galanthamine (Standard)

• UNSPSC Description:

  Galanthamine (Standard) is the analytical standard of Galanthamine. This product is intended for research and analytical applications. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM.

• Target Antigen:

  Apoptosis; Cholinesterase (ChE)

• Type:

  Reference Standards

• Related Pathways:

  Apoptosis;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/galanthamine-standard.html

• Smiles:

  O[C@@H]1C[C@@H]2OC3=C4C(CN(C)CC[C@]42C=C1)=CC=C3OC

• Molecular Weight:

  287.35

• References & Citations:

  [1]Melanie-Jayne R. Howes, et al. Acetylcholinesterase inhibitors of natural origin. International Journal of Research in Pharmaceutical and Biomedical Sciences 3(SI 1):67-86.|[2]Kuryatov A, et al. Roles of accessory subunits in alpha4beta2(*) nicotinic receptors. Mol Pharmacol. 2008 Jul;74(1):132-43.|[3]Kita Y, et al. Galantamine increases hippocampal insulin-like growth factor 2 expression via α7 nicotinic acetylcholine receptors in mice. Psychopharmacology (Berl). 2013 Feb;225(3):543-51.

• Shipping Conditions:

  Room temperature

• CAS Number:

  357-70-0