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N-Desmethyl Bendamustine

CAT: 0804-HY-137200-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-137200-01Size:500 µg
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Description
N-Desmethyl Bendamustine is a metabolite of Bendamustine. N-Desmethyl Bendamustine has cytotoxic effect in several lymphoma cell lines and peripheral blood lymphocytes[1].
CAS Number
41515-13-3
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-desmethyl-bendamustine.html
Smiles
O=C(O)CCCC1=NC2=CC=C(N(CCCl)CCCl)C=C2N1
Molecular Formula
C15H19Cl2N3O2
Molecular Weight
344.24
References & Citations
[1]Jens Teichert, et al. Characterization of two phase I metabolites of bendamustine in human liver microsomes and in cancer patients treated with bendamustine hydrochloride. Cancer Chemother Pharmacol. 2007 May;59 (6) :759-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported