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(S) -EB-FAPI-B2

CAT: 0804-HY-159770A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-159770A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -EB-FAPI-B2 (Compound II-11) is a precursor for radiopharmaceutical labeling, which can be combined with radionuclides to create radionuclide drug conjugates (RDCs) . RDCs have the capability to specifically target biomolecules and can be used in medical imaging or therapy[1][2].
CAS Number
2740747-99-1
UNSPSC
12352203
Target
Radionuclide-Drug Conjugates (RDCs)
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-eb-fapi-b2.html
Smiles
O=S(O)(C1=CC(S(=O)(O)=O)=C(N)C2=C1C=CC(/N=N/C3=C(C=C(C4=CC(C)=C(C=C4)NC([C@H](CCCCNC(CCOCCOCCC(N5CCN(CC5)CCCOC6=CC7=C(N=CC=C7C(NCC(N8[C@@H](CCC8)C#N)=O)=O)C=C6)=O)=O)NC(CN9CCN(CCN(CCN(CC9)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)C=C3)C)=C2O)=O
Molecular Formula
C78H100N16O22S2
Molecular Weight
1677.85
References & Citations
[1]Chen XY, et al. Truncated Evans blue modified fibroblast activation protein inhibitor and preparation method and application thereof. CN113582975A. 2021 November 02.|[2]Wen X, et al. Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics. Theranostics. 2022 Jan 1;12 (1) :422-433.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
Phase 1