BMS 488043

• Description :

  BMS 488043 (BMS 043) is an orally active and well-tolerated inhibitor of the attachment of human immunodeficiency virus type 1 (HIV-1) to CD4+ lymphocytes[1].

• CAS Number :

  [452296-83-2]

• Product Name Alternative :

  BMS 043

• UNSPSC :

  12352005

• Target :

  HIV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/bms-488043.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CNC2=C1C(OC)=CN=C2OC)C(N3CCN(CC3)C(C4=CC=CC=C4)=O)=O

• Molecular Formula :

  C22H22N4O5

• Molecular Weight :

  422.43

• References & Citations :

  [1]George J Hanna, et al. Antiviral activity, pharmacokinetics, and safety of BMS-488043, a novel oral small-molecule HIV-1 attachment inhibitor, in HIV-1-infected subjects. Antimicrob Agents Chemother. 2011 Feb;55 (2) :722-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2