LP-03

• Description :

  LP-03 is an antibacterial agent with selective activity against Methicillin-resistant Staphylococcus aureus (MRSA) . Its minimum inhibitory concentration (MIC) is 6.2 μM. LP-03 has an inhibitory effect on biofilm formation, but it is unable to effectively remove the formed biofilms. LP-03 can enhance membrane permeability, disrupt the membrane structure of MRSA cells, and does not cause significant membrane depolarization. LP-03 has no hemolytic toxicity and shows low mammalian cell toxicity. It can be used for research on MRSA infections[1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  [H][C@]12C(CC[C@]1(C(CC[C@@]3([C@@]2(OC([C@@]34[C@@]5(C(NC6=C5C=C(C=C6)Br)=O)N7CCC[C@H]7C4)=O)[H])[H])=C)[H])=C

• Molecular Formula :

  C27H29BrN2O3

• Molecular Weight :

  509.43

• References & Citations :

  [1]Bhushan A, et al. Selective membrane disrupting dispiro-oxindole Dehydrocostuslactone hybrids with potent anti-MRSA, antibiofilm, and synergistic activity. Bioorg Chem. 2025 Dec;167:109230.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported