LP-03

CAT: 0804-HY-179611Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-179611Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LP-03 is an antibacterial agent with selective activity against Methicillin-resistant Staphylococcus aureus (MRSA) . Its minimum inhibitory concentration (MIC) is 6.2 μM. LP-03 has an inhibitory effect on biofilm formation, but it is unable to effectively remove the formed biofilms. LP-03 can enhance membrane permeability, disrupt the membrane structure of MRSA cells, and does not cause significant membrane depolarization. LP-03 has no hemolytic toxicity and shows low mammalian cell toxicity. It can be used for research on MRSA infections[1].
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
[H][C@]12C(CC[C@]1(C(CC[C@@]3([C@@]2(OC([C@@]34[C@@]5(C(NC6=C5C=C(C=C6)Br)=O)N7CCC[C@H]7C4)=O)[H])[H])=C)[H])=C
Molecular Formula
C27H29BrN2O3
Molecular Weight
509.43
References & Citations
[1]Bhushan A, et al. Selective membrane disrupting dispiro-oxindole Dehydrocostuslactone hybrids with potent anti-MRSA, antibiofilm, and synergistic activity. Bioorg Chem. 2025 Dec;167:109230.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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