1E7-03

• Description :

  1E7-03, a low MW tetrahydroquinoline derivative targeting protein phosphatase-1, can inhibit HIV-1 transcription[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  HIV; Phosphatase

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/1e7-03.html

• Purity :

  95.07

• Solubility :

  DMSO : 20.83 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(C1=C(CC/C2=C\C3=CC=C(OC)C(OC)=C3)C2=NC4=CC=CC=C14)OC(C)C(NC(NCC)=O)=O

• Molecular Formula :

  C28H29N3O6

• Molecular Weight :

  503.55

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Ammosova T, et al. 1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription. Br J Pharmacol. 2014;171 (22) :5059-5075.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1565845-92-2]