DYB-03

CAT: 0804-HY-161313-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-161313-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
DYB-03 is an oral active HIF-1α/EZH2 inhibitor. DYB-03 inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs in vitro and in vivo. DYB-03 induces apoptosis in 2-ME2- and GSK126-resistant of A549 and H460 cells[1].
CAS Number
[2982792-85-6]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase; Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dyb-03.html
Purity
99.49
Solubility
DMSO : ≥ 100 mg/mL
Smiles
COC1=CC=C(/C=C/C(C2=CC=C(OC(C)(C)C=C3)C3=C2O)=O)C=C1OCCCN4CCOCC4
Molecular Formula
C28H33NO6
Molecular Weight
479.56
References & Citations
[1]Wang J, et al. The Interplay Between HIF-1α and EZH2 in Lung Cancer and Dual-Targeted Drug Therapy. Adv Sci (Weinh) . 2024 Feb;11 (7) :e2303904.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-179611LP-03
HY-124644-011E7-03
HY-164425ENT-03
HY-143343LEB-03-153
HY-143340LEB-03-145
HY-111556-01BSJ-03-123
HY-133120-01INY-03-041
HY-153718KI-ARv-03
HY-137346-01DD-03-156
HY-147136-01MYF-03-176

Alternative Products

CatalogName
MF-0147505-01DYB-03
MBS1470180Recombinant Caenorhabditis elegans Dystrobrevin-1 (dyb-1), partial
MBS9015647Rabbit anti-Caenorhabditis elegans dyb-1 Polyclonal Antibody
MBS5814322CInQ-03
MBS5756961WEHL-03
MF-0015759-01TA-03
MBS3602234-011E7-03
TRC-H010305-250MGHostanox 03
MF-0144219-01WEN05-03
452487-01ISCK 03

Popular Products