SR-16434

• Description :

  SR-16434 is a nociceptin/orphanin FQ (NOP) /μ-opioid receptor partial agonist, with high binding affinity (NOP receptor Ki=7.49; μ-Opioid receptor Ki=2.70) . SR-16434 can relieve pain[1].

• Product Name Alternative :

  SR-16435 (free base)

• UNSPSC :

  12352005

• Target :

  Opioid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/sr-16435.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(C2CCN(C3C4CCCC3CCC4)CC2)C5=C(C=CC=C5)C1

• Molecular Formula :

  C22H30N2O

• Molecular Weight :

  338.49

• References & Citations :

  [1]Khroyan TV, et al. SR 16435 [1- (1- (bicyclo[3.3.1]nonan-9-yl) piperidin-4-yl) indolin-2-one], a novel mixed nociceptin/orphanin FQ/mu-opioid receptor partial agonist: analgesic and rewarding properties in mice. J Pharmacol Exp Ther. 2007;320 (2) :934-943.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [857262-16-9]