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Ro 70‐0004

CAT: 0804-HY-105537Size: 1 EachDry Ice: NoHazardous: No
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Description
Ro 70-0004 (RS-100975) is a selective alpha1A-adrenoceptor antagonist with a pKi of 8.9. Ro 70‐0004 can be used in the study of prostatic hyperplasia[1].
CAS Number
186386-21-0
Product Name Alternative
RS-100975
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ro-70-0004.html
Smiles
O=C1NC=C(C)C(N1CCCN2CCN(CC2)C3=CC=C(C=C3OCC(F)(F)F)F)=O
Molecular Formula
C20H24F4N4O3
Molecular Weight
444.42
References & Citations
[1]Williams TJ, et al. In vitro alpha1-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel alpha1A-adrenoceptor selective antagonists. Br J Pharmacol. 1999 May;127 (1) :252-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
α adrenergic receptor

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