RO 4927350

• Description :

  RO 4927350 is a potent and selective non-ATP-competitive MEK1/2 inhibitor. RO 4927350 exhibits significant antitumor efficacy in a broad spectrum of tumor models[1].

• UNSPSC :

  12352005

• Target :

  MEK

• Type :

  Reference compound

• Related Pathways :

  MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ro-4927350.html

• Smiles :

  C[C@@H](C1=CC=CC=C1)[C@H](N2C([C@@H](C3=CC=C(C=C3)OCCO)NC2=O)=O)C(NC4=NC(C(CC)=O)=CS4)=O

• Molecular Formula :

  C27H28N4O6S

• Molecular Weight :

  536.60

• References & Citations :

  [1]Daouti S, et, al. Characterization of a novel mitogen-activated protein kinase kinase 1/2 inhibitor with a unique mechanism of action for cancer therapy. Cancer Res. 2009 Mar 1;69 (5) :1924-32.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [876755-27-0]