RO 4927350

• Description:

  RO 4927350 is a potent and selective non-ATP-competitive MEK1/2 inhibitor. RO 4927350 exhibits significant antitumor efficacy in a broad spectrum of tumor models[1].

• UNSPSC:

  12352005

• Target:

  MEK

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ro-4927350.html

• Smiles:

  C[C@@H] (C1=CC=CC=C1) [C@H] (N2C ([C@@H] (C3=CC=C (C=C3) OCCO) NC2=O) =O) C (NC4=NC (C (CC) =O) =CS4) =O

• Molecular Formula:

  C27H28N4O6S

• Molecular Weight:

  536.60

• References & Citations:

  [1]Daouti S, et, al. Characterization of a novel mitogen-activated protein kinase kinase 1/2 inhibitor with a unique mechanism of action for cancer therapy. Cancer Res. 2009 Mar 1;69 (5) :1924-32.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  876755-27-0