HIF-2α-IN-2

• UNSPSC Description:

  HIF-2α-IN-2 is a hypoxia-inducible factors (HIF-2α) inhibitor extracted from patent WO2015035223A1, Compound 232, has an IC50 of 16 nM in scintillation proximity assay (SPA)[1].

• Target Antigen:

  HIF/HIF Prolyl-Hydroxylase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hif-2-alpha-in-2.html

• Purity:

  99.93

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  N#CC1=CC(OC2=CC=C(S(=O)(C)=O)C3=C2CC(F)C3O)=CC(F)=C1

• Molecular Weight:

  365.35

• References & Citations:

  [1]Darryl David DIXON, et al. Aryl ethers and uses thereof. WO2015035223A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1672666-82-8