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SJPYT-195

CAT: 0804-HY-150616-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-150616-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SJPYT-195 is a cytotoxic GSPT1 degrader and can be used for PROTAC synthesis[1].
CAS Number
2973762-16-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Molecular Glues; Pregnane X Receptor (PXR)
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sjpyt-195.html
Concentration
10mM
Purity
99.41
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(C)N(C2=CC(OC)=CC=C2OC)N=N1)NC3=CC(OC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=CC(C(C)(C)C)=C3
Molecular Formula
C35H34N6O8
Molecular Weight
666.68
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Huber A D, et al. SJPYT-195: A Designed Nuclear Receptor Degrader That Functions as a Molecular Glue Degrader of GSPT1. ACS Medicinal Chemistry Letters, 2022.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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