SJPYT-328

CAT: 0804-HY-169320Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-169320Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SJPYT-328 is a PXR agonsit. PXR plays a major role in drug metabolism and drug-drug interactions[1].
CAS Number
[2998548-72-2]
UNSPSC
12352005
Target
Cytochrome P450; Pregnane X Receptor (PXR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sjpyt-328.html
Smiles
COC1=C(N2C(C)=C(N=N2)C(NC3=C(C=CC(C(C)(C)C)=C3)O[C@@H](CC)CCC)=O)C=C(C(OC)=C1)C
Molecular Formula
C29H40N4O4
Molecular Weight
508.65
References & Citations
[1]Garcia-Maldonado E, et al. Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR. Nat Commun. 2024 May 14;15 (1) :4054.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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