Antibacterial agent 195

• UNSPSC Description:

  Antibacterial agent 195 (compound A20), a Matrine (HY-N0164) derivative, is a potent antibiotic. Antibacterial agent 195 shows antibacterial activity against Gram-positive bacterium (MICS.aureus=0.021 mg/mL; MICP.acnes=0.030 mg/mL), Gram-negative bacterium (MICE.coli=0.092 mg/mL; MICC.albicans=0.379 mg/mL) and Fungus (MIC=2.806 mg/mL)[1].

• Target Antigen:

  Antibiotic; Bacterial; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/antibacterial-agent-195.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC2=C(C=C(CC3=CC=C(C(F)(F)F)C=C3)C=C2)N1)N4[C@@](CCCC(OC)=O)([H])[C@]5([H])[C@](N6CCC5)([H])[C@](CCC6)([H])C4

• Molecular Weight:

  581.67

• References & Citations:

  [1]Yufang Li, et al. Synthesis, antibacterial activity, and 3D-QASR studies of matrine-indole derivatives as potential antibiotics. Bioorg Med Chem Lett. 2024 Feb 21:102:129671.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4