SJPYT-310

• Description:

  SJPYT-310 is a selective PXR antagonist. SJPYT-310 shows no significant cytotoxicity[1].

• UNSPSC:

  12352005

• Target:

  Orphan Receptor; Pregnane X Receptor (PXR)

• Related Pathways:

  GPCR/G Protein; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Others

• Purity:

  99.9

• Smiles:

  CC (C) (C) C1=CC=C (O[C@@H] (C) CCC) C (NC (C2=C (C) N (C3=C (OC) C=CC (C) =C3) N=N2) =O) =C1

• Molecular Formula:

  C27H36N4O3

• Molecular Weight:

  464.60

• References & Citations:

  [1]Garcia-Maldonado E, et al. Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR. Nat Commun. 2024 May 14;15 (1) :4054.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2883814-84-2