SJPYT-310

• Description :

  SJPYT-310 is a selective PXR antagonist. SJPYT-310 shows no significant cytotoxicity[1].

• UNSPSC :

  12352005

• Target :

  Orphan Receptor; Pregnane X Receptor (PXR)

• Related Pathways :

  GPCR/G Protein; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Others

• Purity :

  99.9

• Smiles :

  CC(C)(C)C1=CC=C(O[C@@H](C)CCC)C(NC(C2=C(C)N(C3=C(OC)C=CC(C)=C3)N=N2)=O)=C1

• Molecular Formula :

  C27H36N4O3

• Molecular Weight :

  464.60

• References & Citations :

  [1]Garcia-Maldonado E, et al. Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR. Nat Commun. 2024 May 14;15 (1) :4054.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2883814-84-2]