MSK-195

• Description :

  MSK-195 is a potent agonist of TRPV1, with a potency of 120 nM and an efficacy of 71% in arteriolar response[1].

• CAS Number :

  [289902-82-5]

• UNSPSC :

  12352005

• Target :

  TRP Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/msk-195.html

• Smiles :

  CC(C)(C(OCC(CNC(CC1=CC=C(C(OC)=C1)OCCN)=O)CC2=CC=C(C(C)=C2)C)=O)C

• Molecular Formula :

  C28H40N2O5

• Molecular Weight :

  484.63

• References & Citations :

  [1]Á Czikora, et al. Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1. Br J Pharmacol. 2012 Mar; 165 (6) : 1801–1812.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported