MT 63-78

CAT: 0804-HY-W058849-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W058849-01Size:1 mg
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AVAILABILITY: InStock
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Description
MT 63-78 is a specific and potent direct AMPK activator with an EC50 of 25 μM. MT 63–78 also induces cell mitotic arrest and apoptosis. MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects[1].
CAS Number
[1179347-65-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
AMPK; Apoptosis; mTOR
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mt-63-78.html
Purity
98.00
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
N#CC1=CNC2=C1C=C(C3=CC=C(C4=C(O)C=CC=C4O)C=C3)C=C2
Molecular Formula
C21H14N2O2
Molecular Weight
326.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Zadra G, et al. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014 Apr;6 (4) :519-38.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPK; mTORC1

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