EGFR-IN-115

• UNSPSC Description:

  EGFR-IN-115 (H-13) is an EGFR inhibitor, with IC50 of 395.2 nM. EGFR-IN-115 can be used in anti-cancer research[1].

• Target Antigen:

  EGFR

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/egfr-in-115.html

• Smiles:

  O=C(C1=CN=C(NC2=CC(NC(NC3CCN(C)CC3)=O)=C(N4CCOCC4)C=C2OC)N=C1C5=CN(C)C6=C5C=CC=C6)OC(C)C

• Molecular Weight:

  656.77

• References & Citations:

  [1]Fan D, et al. Design, synthesis, and evaluation of antitumor activity of Mobocertinib derivatives, a third-generation EGFR inhibitor. Bioorg Chem. 2024 Jun;147:107390.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported