TM2-115

• UNSPSC Description:

  TM2-115 inhibits malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death[1].

• Target Antigen:

  Histone Methyltransferase; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Epigenetics

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/tm2-115.html

• Purity:

  98.37

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CN1CCC(NC2=C3C=C(OC)C(OCC4=CC=CC=C4)=CC3=NC(N5CCN(C)CCC5)=N2)CC1

• Molecular Weight:

  490.64

• References & Citations:

  [1]Malmquist NA, et al. Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16708-13.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1197196-47-6