TM2-115

• Description :

  TM2-115 inhibits malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death[1].

• UNSPSC :

  12352005

• Target :

  Histone Methyltransferase; Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Epigenetics

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/tm2-115.html

• Purity :

  98.37

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CN1CCC(NC2=C3C=C(OC)C(OCC4=CC=CC=C4)=CC3=NC(N5CCN(C)CCC5)=N2)CC1

• Molecular Formula :

  C28H38N6O2

• Molecular Weight :

  490.64

• References & Citations :

  [1]Malmquist NA, et al. Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum. Proc Natl Acad Sci U S A. 2012 Oct 9;109 (41) :16708-13.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1197196-47-6]