TM2-115

• Description:

  TM2-115 inhibits malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death[1].

• UNSPSC:

  12352005

• Target:

  Histone Methyltransferase; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Epigenetics

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/tm2-115.html

• Purity:

  98.37

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CN1CCC (NC2=C3C=C (OC) C (OCC4=CC=CC=C4) =CC3=NC (N5CCN (C) CCC5) =N2) CC1

• Molecular Formula:

  C28H38N6O2

• Molecular Weight:

  490.64

• References & Citations:

  [1]Malmquist NA, et al. Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum. Proc Natl Acad Sci U S A. 2012 Oct 9;109 (41) :16708-13.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1197196-47-6