Dapsone hydroxylamine

• UNSPSC Description:

  Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity[1].

• Target Antigen:

  Drug Metabolite; Reactive Oxygen Species

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/dapsone-hydroxylamine.html

• Smiles:

  O=S(C1=CC=C(C=C1)N)(C2=CC=C(C=C2)NO)=O

• Molecular Weight:

  264.30

• References & Citations:

  [1]Albuquerque RV, et al. In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells. PLoS One. 2015 Aug 18;10(8):e0134768.|[2]Wozel G, et al. Dapsone hydroxylamine inhibits the LTB4-induced chemotaxis of polymorphonuclear leukocytes into human skin: results of a pilot study. Inflamm Res. 1997 Oct;46(10):420-2.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  32695-27-5