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N-Acetyl dapsone

CAT: 0804-HY-G0016-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-G0016-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-Acetyl dapsone (MADDS) is the major metabolite of Dapsone. Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1][2].
CAS Number
565-20-8
Product Name Alternative
MADDS; Monoacetyldapsone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n-acetyl-dapsone.html
Solubility
10 mM in DMSO
Smiles
CC(NC1=CC=C(S(=O)(C2=CC=C(N)C=C2)=O)C=C1)=O
Molecular Formula
C14H14N2O3S
Molecular Weight
290.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Tanaka K, et al. Mutagenicity of N-acetyl and N, N'-diacetyl derivatives of 3 aromatic amines used as epoxy-resin hardeners. Mutat Res. 1985 May-Jun;143 (1-2) :11-5.|[2]Bonde S L, et al. Simultaneous determination of dapsone and its major metabolite N-Acetyl Dapsone by LC-MS/MS method. Int. J. Pharm. Pharm. Sci, 2013, 5: 441-446.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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