IHMT-MST1-39

IHMT-MST1-39

• CAS Number: 2414484-01-6
• UNSPSC Description: IHMT-MST1-39 is an orally active inhibitor for MST kinase, with IC50 of 42 nM and 109 nM, for MST1 and MST2. IHMT-MST1-39 activates the AMPK signaling pathway in liver cells, reduces apoptosis of pancreatic β-cells. IHMT-MST1-39 ameliorates diabetes in Streptozotocin (HY-13753)-induced type 1 diabetes (T1D) mouse models[1].
• Target Antigen: AMPK; Apoptosis; Hippo (MST)
• Type: Reference compound
• Related Pathways: Apoptosis;Epigenetics;PI3K/Akt/mTOR;Stem Cell/Wnt
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/ihmt-mst1-39.html
• Smiles: O=C1N(C)C2=CN=C(NC3=CC=C(S(=O)(N)=O)C=C3)N=C2N(C1C4=C(F)C=CC=C4F)C
• Molecular Weight: 460.46
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported