Products for Research Use Only
RegisterLogin

IHMT-RAF-128

CAT: 0804-HY-164484Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-164484Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
IHMT-RAF-128, a highly potent pan-RAF inhibitor. IHMT-RAF-128 shows potent antitumor efficacy in xenograft mouse tumor models without causing any apparent toxicities[1][2].
CAS Number
2479289-15-9
UNSPSC
12352005
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ihmt-raf-128.html
Smiles
FC(F)(F)C1=CC(C(NC2=CC(N3N=CC(C4=CC(N5CCOCC5)=CN=C4)=C3)=C(C)C=C2)=O)=CC=C1
Molecular Formula
C27H24F3N5O2
Molecular Weight
507.51
References & Citations
[1]Olaoba OT, et al. Driver Mutations in Pancreatic Cancer and Opportunities for Targeted Therapy. Cancers (Basel) . 2024 May 9;16 (10) :1808.|[2]Wang A, et al. Discovery of a highly potent pan-RAF inhibitor IHMT-RAF-128 for cancer treatment. Eur J Pharmacol. 2023 Aug 5;952:175752.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-174142IHMT-15130
HY-146697IHMT-TRK-284
HY-162848IHMT-PI3K-315
HY-149493IHMT-PI3K-455
HY-156292IHMT-EZH2-426
HY-151257-01IHMT-MST1-58
HY-164595-01IHMT-MST1-39
HY-131910-01IHMT-PI3Kδ-372
HY-149359IHMT-IDH1-053
HY-131910A-01(R) -IHMT-PI3Kδ-372

Alternative Products

CatalogName
T210891-01IHMT-15130
BA7284-5.1IHMT-PI3Kδ-372
BA9065-5.1IHMT-MST1-58
T79780-01IHMT-EZH2-426
MBS5820420IHMT-IDH1-053
T200165-01IHMT-PI3K-315
MBS5802441IHMT-PI3Kdelta-372
MBS5805751IHMT-TRK-284
T78836-01IHMT-PI3K-455

Popular Products