SB-216641

CAT: 0804-HY-W903631Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W903631Size:1 Each
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Description
SB-216641 is a selective 5-HT1b antagonist. SB-216641 mildly prevents stress-induced behavioral performance dysregulations[1][2].
CAS Number
[170230-39-4]
UNSPSC
12352100
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C1=CC=C(C2=C(C)C=C(C3=NOC(C)=N3)C=C2)C=C1)NC4=CC=C(C(OCCN(C)C)=C4)OC
Molecular Formula
C28H30N4O4
Molecular Weight
486.56
References & Citations
[1]Taylor R M, et al. Systemic Administration of the 5-HT1b Antagonist SB-216641 Prior to Acute Stress Exposure in Rats Mildly Prevents Stress-induced Behavioral Performance Dysregulations[J]. The Journal of Pharmacology and Experimental Therapeutics, 2024, 389: 115.|[2]Price GW, et al. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356 (3) :312-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor

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