(S) -Thalidomide-5-OH

• Description:

  (S) -Thalidomide-5-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. (S) -Thalidomide-5-OH can be linked to a target protein ligand via a linker to form a PROTAC.

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H361-H373

• Target:

  Ligands for E3 Ligase

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C1N(C(=O)C=2C1=CC(O)=CC2)[C@@H]3C(=O)NC(=O)CC3

• Molecular Formula:

  C13H10N2O5

• Molecular Weight:

  274.23

• Precautions:

  P264-P270-P280-P405-P501

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound2

• Clinical Information:

  No Development Reported

• Isoform:

  Cereblon

• CAS Number:

  [172333-29-8]