Thalidomide-pinacolborane

• Description :

  Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic pinacol ester, otherwise known as a Bpin group, and they are most frequently used in Suzuki reactions. This molecule is an activator for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Ligands for E3 Ligase

• Related Pathways :

  PROTAC

• Field of Research :

  Cancer

• Purity :

  97.0

• Smiles :

  O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(B4OC(C)(C)C(C)(C)O4)=C3)=O

• Molecular Formula :

  C19H21BN2O6

• Molecular Weight :

  384.19

• Precautions :

  H302, H315, H319, H335

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2229725-98-6]