Thalidomide-pinacolborane

• Target :

  Ligand for E3 Ligase

• Related Pathways :

  PROTAC

• Bioactivity :

  Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic acid pinacol ester, also known as a Bpin group, commonly used in Suzuki reactions. The molecule acts as an activator of E3 ligase, facilitating the ubiquitination of proteins, thereby targeting them for proteolytic degradation.

• Smiles :

  O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)B4OC(C)(C)C(O4)(C)C

• Molecular Formula :

  C19H21BN2O6

• Molecular Weight :

  384.191

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2229725-98-6