TRX-518

CAT: 0804-HY-P991180-01Size: 1 mgDry Ice: YesHazardous: No
CAT#:0804-HY-P991180-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TRX-518 is a humanized agonist antibody targeting glucocorticoid-induced tumor necrosis factor receptor (GITR) . TRX-518 specifically targets GITR⁺ Tregs and CD45RA⁻Foxp3⁺ effector Tregs (eTregs) among regulatory T cells (Tregs), reducing the number of Tregs in circulation and within tumors. TRX-518 is promising for research of cancers[1].
UNSPSC
12352203
Target
TNF Receptor
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.58
Smiles
[3H][R][X518]
Molecular Weight
(145.26 kDa)
References & Citations
[1]Zappasodi R, et al. Abstract CT018: Intratumor and peripheral Treg modulation as a pharmacodynamic biomarker of the GITR agonist antibody TRX-518 in the first in-human trial[J]. Cancer Research, 2017, 77 (13_Supplement) : CT018-CT018.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1

Related Products

CatalogName
HY-13546ABT-518
HY-19668SGS-518
HY-129474MP 518
HY-161307-01T-518
HY-19127FK-518
HY-W952995CRBN ligand-518
HY-P1837Influenza HA (518-526)
HY-D1254-01Trx-red
HY-160414-01TRX-COBI
HY-P7621ABCB5, Human (Trx)

Alternative Products

CatalogName
T9901A-852-01TRX-518
MBS131638-01RX-518
MBS5812049ABT-518
MBS5778442SGS-518
T87488-01T-518
sc-101277ACBD3 (518)
T203179-01MP 518
MBS5757816SGS 518 oxalate
A24070-5T-518 5mg
ANTY021258Merlin (Ab-518)

Popular Products