MP 518

• Description :

  MP 518 is a PDE inhibitor with antihypertensive properties. MP 518 can inhibit cAMP degradation, causing an increase in ICa, and can also antagonize β-adrenergic stimulation, exerting vasodilation[1].

• CAS Number :

  [122432-93-3]

• UNSPSC :

  12352005

• Target :

  Phosphodiesterase (PDE)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/mp-518.html

• Smiles :

  O=C(N/N=C(C1=CC=CC=C1Cl)\C)CO

• Molecular Formula :

  C10H11ClN2O2

• Molecular Weight :

  226.66

• References & Citations :

  [1]Scamps F, et al. Effect of an antihypertensive hydrazine derivative on Ca2+ current of single frog cardiac cells. Eur J Pharmacol. 1993 Jan 15;244 (2) :119-23.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported