MP 518

• Description:

  MP 518 is a PDE inhibitor with antihypertensive properties. MP 518 can inhibit cAMP degradation, causing an increase in ICa, and can also antagonize β-adrenergic stimulation, exerting vasodilation[1].

• UNSPSC:

  12352005

• Target:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/mp-518.html

• Smiles:

  O=C(N/N=C(C1=CC=CC=C1Cl)\C)CO

• Molecular Formula:

  C10H11ClN2O2

• Molecular Weight:

  226.66

• References & Citations:

  [1]Scamps F, et al. Effect of an antihypertensive hydrazine derivative on Ca2+ current of single frog cardiac cells. Eur J Pharmacol. 1993 Jan 15;244 (2) :119-23.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [122432-93-3]