T-518

• CAS Number :

  2276680-91-0

• Target :

  HDAC

• Related Pathways :

  DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Bioactivity :

  T-518, an orally active and selective HDAC6 inhibitor with an IC50 value of 36 nM for human HDAC6, can permeate the blood-brain barrier and is applicable in tauopathy research [1].

• Smiles :

  O=C1N(CC=2C1=CC(=CN2)C=3OC(C(F)F)=NN3)[C@H]4[C@H](NC(C(C(F)(F)F)(F)F)=O)CCCC4

• Molecular Formula :

  C19H16F7N5O3

• Molecular Weight :

  495.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C