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SGS-518

CAT: 0804-HY-19668Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19668Size:1 Each
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Description
SGS-518 is a selective 5-HT6R antagonist. SGS518 can be used for the research of cognitive impairments such as amnesia, anxiety and depression, and it is effective in protecting mouse retina at high doses[1].
CAS Number
445441-26-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=S(OC1=CC(C(C2CCN(CC2)C)=CN3C)=C3C=C1)(C4=C(F)C=CC=C4F)=O
Molecular Formula
C21H22F2N2O3S
Molecular Weight
420.47
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Chen Y, et, al. Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration. J Clin Invest. 2013 Dec; 123 (12) : 5119-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT6 Receptor

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