RegisterLogin

Tz-Thalidomide (Standard)

CAT: 0804-HY-101460RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-101460RSize:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Tz-Thalidomide (Standard) is the analytical standard of Tz-Thalidomide (HY-101460) . This product is intended for research and analytical applications. Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase) . Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2) . Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups[1].
CAS Number
[2087490-42-2]
Target
Epigenetic Reader Domain; Molecular Glues; PROTACs; Reference Standards
Related Pathways
Epigenetics; Others; PROTAC
Field of Research
Cancer
Smiles
O=C(CCCCCOC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1)NCC(C=C4)=CC=C4C5=NN=C(C)N=N5
Molecular Formula
C29H29N7O6
Molecular Weight
571.58
References & Citations
[1]Lebraud H, et al. Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras. ACS Cent Sci. 2016 Dec 28;2 (12) :927-934.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-101460-01Tz-Thalidomide
HY-14658R-01Thalidomide (Standard)
HY-23095R-01Thalidomide-5-OH (Standard)
HY-155370IR808-TZ
HY-157316TZ-NBD
HY-160258GDP-Fucose-Tz
HY-160298GDP-Fuc-Tz
HY-151686-01Bz- (Me) Tz-NHS
HY-151730(Me) Tz-butanoic acid
HY-14658-01Thalidomide

Alternative Products

CatalogName
BUP06027-01Tz-Thalidomide
A24497-100Tz-Thalidomide 100mg
A24497-5Tz-Thalidomide 5mg
A24497-50Tz-Thalidomide 50mg
A24497-10Tz-Thalidomide 10mg
T208747-01TZ-NBD
OR1078690-01B-Tz
152139Tartrazine (TZ)
T82053-01IR808-TZ
abx100297-01Tartrazine (TZ) Antibody

Popular Products