Products for Research Use Only
RegisterLogin

SR 47063

CAT: 0804-HY-19138Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-19138Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SR 47063 is an ATP-sensitive potassium channel (KATP) agonist. SR 47063 selectively activates KATP channels in vascular smooth muscle cells (IC50: 8.1 nM in human saphenous vein, 3.86 nM in rat aorta) . SR 47063 promotes potassium efflux and cellular hyperpolarization to induce vasorelaxation. SR 4706 is promising for research of hypertension and related cardiovascular disorders[1].
CAS Number
135809-60-8
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Smiles
N#C/N=C1C=CC=CN\1C2=CC(C)(C)OC3=C2C=C([N+]([O-])=O)C=C3
Molecular Formula
C17H14N4O3
Molecular Weight
322.32
References & Citations
[1]Criddle DN, et al. Vasorelaxant effects of the potassium channel opener SR 47063 on the isolated human saphenous vein and rat aorta. Braz J Med Biol Res. 2000 Aug;33 (8) :961-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

Related Products

CatalogName
HY-111953-01SR-4559
HY-179514Gala-SR
HY-18345-01SR 49059
HY-111400-01SR-4370
HY-160162-01SR 11023
HY-16469SR 13668
HY-11077-01SR 146131
HY-105259SR 43845
HY-P2130SR 42128
HY-120144SR-8993

Popular Products