HDAC-IN-97

• Description:

  HDAC-IN-97 is a PROTAC HDAC6 degrader-6that can be used for synthesis of PROTACs, such as HDAC6 degrader-6 (HY-177758) . HDAC6 degrader-6 is a potent HDAC6 PROTAC degrader with anticancer activity[1].

• UNSPSC:

  12352211

• Target:

  HDAC; Ligands for Target Protein for PROTAC

• Related Pathways:

  Cell Cycle/DNA Damage; Epigenetics; PROTAC

• Field of Research:

  Cancer

• Smiles:

  O=C(CCCCCCC(O)=O)NO

• Molecular Formula:

  C8H15NO4

• Molecular Weight:

  189.21

• References & Citations:

  [1]Yang K, et al. A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders. Cell Chem Biol. 2020 Jul 16;27 (7) :866-876.e8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [149647-86-9]