EEF2K degrader-2

• Description :

  EEF2K degrader-2 is a molecular glucose degrading agent that targets the eEF2K protein. eEF2K degrader-2 can significantly inhibit the proliferation, migration, invasion and induce apoptosis of triple negative breast cancer (TNBC) cells. eEF2K degrader-2 has no obvious organ toxicity or pathological damage. eEF2K degrader-2 can be used in the research of cancer such as breast cancer[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; CaMK; Molecular Glues

• Related Pathways :

  Apoptosis; Neuronal Signaling; PROTAC

• Field of Research :

  Cancer

• Smiles :

  FC1=CC(CN(C2=O)C(C(C(N3CC(C(OCC)=O)CCC3)=O)=NN2C4=CC=C(C(C)=C4)C)=O)=CC=C1

• Molecular Formula :

  C27H29FN4O5

• Molecular Weight :

  508.54

• References & Citations :

  [1]Zhong C, et al. Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer. Adv Sci (Weinh) . 2024 Feb;11 (5) :e2305035.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1044797-96-7]